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keisanHigh-precision calculations for everyday life and work

Simulation of Blood Concentrations Following Drug Administration

Author: TaikiIkekameExecutions: 30914

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This graph illustrates the steady state achieved with a single dose and repeated doses at equal intervals up to four times a day.
Maximum time
h
Half-life
h
Maximum concentration
ng/mL
Number of doses
Caffeine (60 mg), time to peak: 1.2 h, half-life: 6.6 h, peak concentration: 8,200 ng/mL

Acetaminophen (400 mg), time to peak: 0.46 h, half-life: 2.36 h, peak concentration: 9,100 ng/mL

Ibuprofen (200 mg), time to peak: 2.1 h, half-life: 3.4 h, peak concentration: 16,600 ng/mL

Loxoprofen sodium (60 mg), time to peak: 0.45 h, half-life: 1.22 h, maximum concentration: 5,040 ng/mL

Epinastine hydrochloride (20 mg), time to peak: 1.9 h, half-life: 12.1 h, peak concentration: 33,000 ng/mL

Loratadine (10 mg), time to peak: 1.6 h, half-life: 14.3 h, peak concentration: 7,730 ng/mL

Fexofenadine hydrochloride (60 mg), time to peak: 2.2 h, half-life: 9.6 h, peak concentration: 248 ng/mL

Cetirizine hydrochloride (20 mg), time to peak: 1.50 h, half-life: 6.79 h, peak concentration: 438 ng/mL

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